1.基本信息
孙健,男,1987年11月生,河北省衡水人,水生生物学博士,博士后,副教授。
2.教育经历
2015-9至2019-6, 西北农林科技大学水生生物学专业获博士学位;
2011-9至2014-6, 华中农业大学水产养殖专业获硕士学位;
2006-9至2010-6, 西北农林科技大学水产养殖专业获学士学位。
3.研究方向
水产动物脂质蓄积营养调控
4.获得奖励
2021年,陕西高等学校科学技术奖二等奖(排名第2)
5.主持或参与项目
(1) 国家自然科学基金委员会,青年科学基金项目,32002403,高脂通过HIF1-α双向调控ATGL诱导草鱼脂肪细胞增大和增生的分子机制,2021-01至2023-12,24万元,在研,主持。
(2) 中国博士后科学基金,面上一等资助,2019M660266,草鱼GPR133感知DHA靶向ATGL促进脂肪细胞脂解的机制,2019-09至2021-06,12万元,已结题,主持。
(3) 国家自然科学基金委员会,面上项目, 31772863,内质网应激参与DHA促进草鱼脂肪细胞脂解过程的机制研究,2018-01至2021-12,61万,在研,参与。
(4) 国家自然科学基金委员会,面上项目, 32072989,DHA通过PPARγ-NIX/BNIP3信号轴介导的线粒体自噬调控草鱼脂肪细胞凋亡的机制分析,2021-01至2024-12,58万,在研,参与。
6. 代表性论文
(1) Sun J, Wu WY, Xu XX, Ji H. 2021. DGAT1 protects against lipid induced-hepatic lipotoxicity in grass carp ( Ctenopharyngodon idellus ).Aquaculture, 534, 736328.
(2) Sun J, Huang XC, Ji SH, Ji H. 2019. Two faces of PPARα/NFκB Signaling pathway in inflammatory responses to adipocytes lipolysis in grass carp Ctenopharyngodon idella . Fish and Shellfish Immunology, 90: 244-249.
(3) Sun J, Bian CC, Ji SH, Luo XL, Ji H. 2019. Greater potency of adipocytes compared with preadipocytes under lipopolysaccharide exposure in grass carp Ctenopharyngodon idella . Fish and Shellfish Immunology, 91: 343-349.
(4) Sun J, Xu XX, Huang XC, Ji SH, Bian CC, Ji H. 2020. Nuclear factor-κB subunit p65 is involved in lipopolysaccharide-induced lipid accumulation via regulating DGAT1b in Ctenopharyngodon idellus kidney cells. Fish and Shellfish Immunology, 105:71-77.
(5) Sun J, Li HD, Luo XL, Lu RH, Ji H. 2020. Identification, characterization of two isoforms of acyl-coenzyme A oxidase 1 gene and their expression in fasting-induced grass carp Ctenopharyngodon idella adipocyte lipolysis. Fish Physiology and Biochemistry, 46: 1645-1652.
(6) Sun, J., Deng, W., Gou, N. N., Ji, H., Du, Z. Y., Chen, L. Q. 2019. CIDEA and CIDEC are regulated by CREB and are not induced during fasting in grass carp Ctenopharyngodon idella adipocytes. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 234: 50-57.
(7) Sun J, Yang Z, Shi XC, Ji H, Du ZY, Chen LQ. 2018. G0S2a1 (G0/G1 switch gene 2a1) is downregulated by TNF-α in grass carp ( Ctenopharyngodon idellus ) hepatocytes through PPARα inhibition. Gene, 641: 1-7.
(8) Sun J, Xiao PZ, Chang ZG, Ji H, Du ZY, Chen LQ. 2017. Forkhead box O1 in grass carp Ctenopharyngodon idella : Molecular characterization, gene structure, tissue distribution and mRNA expression in insulin-inhibited adipocyte lipolysis. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 204:76-84.
(9) Sun J, Yang Z, Xiao PZ, Liu Y, Ji H, Du ZY, Chen LQ. 2017. Two isoforms of hormone-sensitive lipase b are generated by alternative exons usage and transcriptional regulation by insulin in grass carp ( Ctenopharyngodon idella ). Fish Physiology and Biochemistry, 43(2): 539-541.
(10) Sun J, Ji H, Li XX, Shi XC, Du ZY, Chen LQ. 2016. Lipolytic enzymes involving lipolysis in Teleost: Synteny, structure, tissue distribution, and expression in grass carp ( Ctenopharyngodon idella ). Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 198: 110-118.
7.联系方式
通讯地址:陕西省杨凌农业高新技术产业示范区西农路22号
邮编:712100
电子邮箱:Email: sunnjjian@nwafu.edu.cn;sunnjjian@163.com